by Elio
If your answer is Alexander Fleming or Selman Waxman, you would be off by about 50 million years.
The answer is insects. There are ants and wasps that cultivate antibiotic producing bacteria and use them to preserve their caches of food. The classic example is the leaf-cutting ants which feed on fungi they cultivate on the well-chewed vegetable matter they bring to their nest. Well-chewed bits of leaves and flowers should, by rights, be the perfect substrate for the growth of all kinds of fungi. Not so. Only the one fungus that the ants prefer makes it. Other fungi are inhibited by an antifungal antibiotic made by bacteria that the ants carry on their cuticle.
Now a new story (link updated in 2014) has emerged. A wasp, the European beewolf, harbors antifungal-producing bacteria in the glands of their antennae and use them to inoculate their nests, thus protecting their young from infection.
In other words, by the time mammals appeared on earth, ants and wasps were already using antibiotics.
I'll be quite surprised if we don't find a similar phenomenon in even older branches of the tree of life, particularly marine organisms. Everything from sponges to shrimp has to survive in a bath of bacteria and protozoa.
You are so right. A good example are sponges. For an example of work in Australia, see http://www.abc.net.au/science/news/health/HealthRepublish_195275.htm
Elio
Posted by: Alan Dove | May 18, 2007 at 05:55 AM