What is it about the cyclic nature of nucleotides, both monomers and dimers, that makes them such favorites for signaling purposes?
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A good signal molecule must be chemically unstable - easily and spontaneously degraded into non-signal. After all, you don't want your signal receptors to be getting all excited about yesterday's news. Phosphate di-esters are easily hydrolysed. Also, easy to manufacture with enzymes that are just one evolutionary tweak away from existing enzymes.
Posted by: Perplexed in Peoria | September 08, 2010 at 08:34 AM