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I'm curious: are there barriers to interspecies mating between Candida sp? The mechanism seems like it might also be more permissive to gene flow between genetically distinct lines than other organisms, particularly when different chromosome numbers meet up.

I thought of this because of something that puzzles me about us non-microbes. Among primates, for example, how did species-level differences in chromosome number first appear? It seems like the first individual with one more (or one less) chromosome wouldn't be able to mate successfully (due to lack of partners with homologous chromosomes in the same number) and pass along the new pattern.

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