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Within a group of well-studied DNA-based microbes (phages, bacteria, and eukaryotes), genome sizes are found to vary by almost four orders of magnitude. Their rates of mutation per base pair also vary by about that much, so the net result is that their mutation rates per genome vary less than 10-fold. Why do you think this is?
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probably a little late to add a comment, but just in case ...
CHIMERAS posted about research showing that the nucleosomes of eukaryotes serve to reduce mutation rate. Here's an example of "mechanisms for reducing or repairing mutations" in nuclear DNA that I suggested in my earlier comment.
http://chimerasthebooks.blogspot.com/2012/03/how-nucleosomes-protect-our-dna.html
Posted by: Hollis | March 12, 2012 at 08:22 AM