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Anthony Vecchiarelli

This is fascinating. Current Min models propose that the system can "find" the long-axis of the cell, and use it as a spatial cue for mid-cell positioning of the divisome. Cell-free reconstitution suggests "geometry sensing" is inherent in the biochemistry, while other models show cardiolipin and curvature at the cell poles as "ultimate" cues for long-axis positioning. Short axis cell-division (and nucleoid segregation?!) has significant implications in understanding how stuff is spatially organized in different bacteria. There are so many questions to ask and I can't wait to see how the story unfolds.

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