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Bob Blasdel

One of my favorite things to do with students is show T4 infection under a phase contrast scope to really dramatically demonstrate how very little simple things like a 151 AA long protein can have massive complex effects and give a visceral sense for the majestic brutality of lytic phage infection. Where just a couple of minutes into infection, T4 produces enough Ndd to drag the entire nucleoid mass to the sides of the cell - visible in real time.

Ndd, the Bacteriophage T4 Protein That Disrupts the Escherichia coli Nucleoid, Has a DNA Binding Activity: ">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC107561/

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