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Here is my question-- would the increased killing ability of this combination heighten the risk of the negative side effects of antibiotics, say, by more effectively disrupting the healthy microbiome? If so, what would be the best way to mitigate that... could we reasonably supply one or both of the drugs at/near the site of infection, to limit damage to the rest of the body, or would post-antibiotic treatment with probiotics of some kind be sufficient?

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