Small Things Considered

On the Source of the Black Death

by Roberto  
Yersinia pestis. How immediate our reaction can be to the species name of this bacterium, making us conjure up images of pestilence. As its discoverer, Alexander Yersin, wrote in 1894 of an outbreak of bubonic plague in Hong Kong, this is the "bacille de la peste." (Working independently, Kitasato Shibasaburo also characterized the plague bacterium at nearly the exact same time.) Read more →

Molecular Fossils of Microbial Interactions

by Einat Segev  
Microbes have inhabited our planet for many millions of years. While thriving and dying in almost every niche on Earth, microbes leave behind relics, and some of these relics remain preserved in the geological record. Many cell components are rapidly degraded and do not persist but remains that do are like archives of ancient microbial life. Read more →

Green Sloths and Robots

by Roberto
... in the case of red par­rot feath­ers the pig­ment has the ad­ded be­ne­fit of pro­tect­ing the plu­mage from bac­te­ri­al de­gra­da­tion. To­day I stay on the to­pic of ani­mal co­lor­a­tion by de­scrib­ing the pe­culi­ar pe­lage pig­ment of sloths. Exact­ly what con­sti­tutes an eye-catch­ing color is, of course, in the eye of the be­holder. Read more →

Thinking outside the rod (or coccus)

by Roberto  
With kind per­mis­sion by the or­gan­i­zers, we re­pro­duce here an edit­ed tran­script of Ro­ber­to's talk (via live vi­deo) at the meet­ing on 'Ma­jor ideas in quan­ti­ta­tive mi­cro­bi­al phy­sio­lo­gy: Past, Pre­sent and Fu­ture', held in June this year in Køben­havn, Den­mark. Read more →

Otherlands' Tour of Microbes Through Prehistory

by Janie  
"It is the crucial paradox at the heart of paleontology that practically all our information about life comes only from death." This line from Thomas Halliday's Otherlands, of course, refers to the fossil record. So, it stands to reason that the entire field of paleontology is contingent upon microbes... Read more →

In one step from commensal to mutualist (almost), part 2|2

by Christoph  
I had concluded the first part by say­ing that I would now dis­cuss what mu­ta­tions Ko­ga et al. (2022) found in two mu­ta­tor E. coli line­ages that al­lowed the bac­te­ria to suc­cess­ful­ly "take over" from Pan­toea sp. as sym­bionts in Plau­tia sta­li stink­bugs (termed "im­prov­ed" line­ages.) Here we go... Read more →

In one step from commensal to mutualist (almost), part 1|2

by Christoph  
It is as true as it is, well, bor­ing to keep say­ing that Esch­eri­chia co­li is the best un­der­stood uni­cel­lu­lar or­gan­ism, and the most-stud­ied with ~41,000 tag­ged en­tries in Pub­Med since 1932. But then, every five years or so, comes a sur­prise of what un­ex­pec­ted feats this un­as­sum­ing bac­te­ri­um is cap­able of. Read more →

Evolution-Proofing Antibiotics

by Vilhelmiina Haavisto  
Since the dis­co­ve­ry of pe­ni­cil­lin and its de­vel­op­ment in­to a the­ra­peu­tic agent, an­ti­bio­tics have re­vo­lu­tion­ized me­di­cine and saved count­less lives. How­ever, the way we use these life-sav­ing me­di­cat­ions is fun­da­men­tal­ly un­sus­tain­able as pa­tho­gens ra­pid­ly evolve re­sist­ance, ren­der­ing ma­ny se­ri­ous in­fect­ions ef­fect­ive­ly un­treat­able. Read more →

Why Calcify?

by Roberto  
Janie's re­cent Bio-Brick post, where she in­tro­duces mi­cro­bi­al­ly in­duced cal­cite pre­ci­pi­ta­tion, prompt­ed me to con­tinue on the to­pic. In con­trast to the amor­phous chalk Janie de­scribed, which is pro­duced by bac­te­ria from lime­stone, I'll be de­scrib­ing a ve­ry dif­ferent sort of chalk. Still cal­cium car­bo­nate, but with a com­ple­te­ly dif­fer­ent ge­ne­sis. Read more →

Transient Thoughts on Transduction

by Roberto  
What with the all the talk about CRISPR, the renewed interest in phage therapy, the widespread occurrence of huge phages (to mention but a few of the reasons phage are constantly in the news these days), it's no exaggeration to say that once again in biology "phage are all the rage"... Read more →