Small Things Considered

TWiM #209: Resuscitating persisters and flagellotrophic phage

The TWiM team reveals how ribosome modification resuscitates bacterial persister cells, and explain how a phage tail fiber protein exploits rotation of flagella to move towards the cell membrane. Read more →

mRNA in E. coli : Not Lost Without Translation

by Roberto | Every now and then, a new fin­ding seems to come out of no­where, great­ly chal­len­ging pri­or ideas. Such might be the case on how we came to gain new know­ledge re­gar­ding the struc­tu­ral or­ga­ni­za­tion of the ba­sic pro­ces­ses of tran­scrip­tion and trans­la­tion in Esche­ri­chia coli. Read more →

Happy Thirteenth Birthday Small Things Considered!

by Elio and Roberto | This coming Sunday, December 1st, we'll be celebrating the thirteenth birthday of STC. Now a teenager! The blog has matured to over 1300 posts, two per week with virtually no interruptions. This is something that makes us very happy. When we think about it, if we were to print all those posts on standard letter size paper... Read more →

Forbearance with the Escherichia coli Nucleoid

by Conrad Woldringh | Adding to the enormous existing literature, the Dekker group recently produced two articles using their ability to visualize a ring-like nucleoid and to study its properties and dynamics during rest and replication. How did they obtain such a ring-like structures? They reasoned that the normal rod-shaped E. coli cell was too thin to allow direct clear visualization of its nucleoid. Read more →

Talmudic Question #171

by Ellie Arrington
Why are Gammaproteobacteria the weeds of microbial communities? Read more →

A sprinkle of acid a day keeps the law enforcement away

by Aleks Prochera | Imagine you look like someone dangerous, a criminal, an enemy. Despite being an exemplary citizen, you have to deal with the possibility that, at one point or another, you might get in trouble with law enforcement simply because you appear threatening. That's a struggle that many bacterial members of a plant's microbiome face. Read more →

Must Read – Time to Cut Down the Tree of For-Profit Science Publishing

by Roberto | Here at STC we have covered the growing problems with the way that scientific publishing has evolved over the past few deca­des. Two instances come to mind, a conversation I held with George O'Toole and a recent praise of the eLife model as a step in the right direction to alleviate some of the problems. Our voices... Read more →

To grow or not to grow? That is the question!

by Roberto | What happens to bacterial populations as they transition from a state of rapid growth to little or no growth as a consequence of diminishing amounts of nutrients? It seems that every time this quest­ion is addressed in a new setting and/or a different species, some fas­cinating new features of bacterial adaptability are discovered. Read more →

TWiM #208: Georgia Tech microbial

At Georgia Tech, members and trainees of the Center for Microbial Dynamics and Infection discuss the identification of pathogen essential genes during coinfections, and how coral management can improve coral defenses against pathogens. Read more →

The Continuing Saga of Insect-Associated Streptomyces

by Roberto | For some reason that I cannot really pinpoint, I am con­ti­nu­ally fascinated by the interactions that are continually discovered between insects and bacteria. Among some of my favorites are those that involve insects that carry bacteria that produce antimicrobial com­pounds that in turn provide a useful function for the insect.
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